GC–MS Profiling and Phytochemical Characterization of Bioactive Constituents in Macaranga peltata Leaf Powder

Author(s): DS Warange and VS Chavan

Abstract:

Macaranga peltata (Roxb.) Müll.Arg. is an ethnomedicinal plant belonging to the family Euphorbiaceae widely distributed in tropical forests of India and Sri Lanka. Traditionally, the plant is used in indigenous medicine for the treatment of fever, wounds, ulcers, and inflammatory disorders. Recent studies report antioxidant and anticancer potential of M. peltata leaf extracts. The present study aimed to characterize the phytochemical constituents present in Macaranga peltata leaf powder using Gas Chromatography–Mass Spectrometry (GC–MS). GC–MS analysis revealed twenty-nine phytochemical constituents with diverse retention times and peak area percentages. The major compounds identified were 2-Chloroethyl methyl sulfoxide (22.73%), Ginsenol (6.67%), 2,6-Dibromo-3-trifluoromethyl-4-nitrophenyl-.beta.-phenylpropionate (5.15%), and Z,Z-3,13-Octadecedien-1-ol (4.96%). The presence of alcohols, esters, phenolics, fatty acids, and heterocyclic compounds indicates the medicinal importance of M. peltata leaves. These findings support the traditional therapeutic applications of the plant and suggest its pharmaceutical potential.

keywords:
Macaranga peltata, GC–MS, phytochemical analysis, leaf powder.

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