Anti-Microbial Activity of Silver Metal Complex (OMC)

Author(s): Dr. Shanta Bellani and Dr. Harsha Premchandani

Abstract:

The antimicrobial activity of silver metal complexes has gained considerable interest due to their potential applications in various fields, including medicine, agriculture, and water treatment. This abstract provides an overview of recent research exploring the antimicrobial properties of silver metal complexes and their mechanisms of action. Silver metal complexes have shown broad-spectrum antimicrobial activity against a wide range of bacteria, fungi, and viruses. This activity is attributed to the release of silver ions from the metal complex, which interact with microbial cells and disrupt their vital processes. Various types of silver metal complexes, including silver nanoparticles, silver ions coordinated with organic ligands, and silver chelates with different metals, have been investigated for their antimicrobial properties. The mode of action and efficacy of these complexes can be influenced by factors such as the nature of the ligands, the size and shape of the nanoparticles, and the presence of other metals. The antimicrobial activity of silver metal complexes has been demonstrated against both drug-sensitive and drug-resistant microbial strains. Studies have shown their effectiveness in inhibiting the growth of multidrug-resistant bacteria, such as methicillin-resistant Staphylococcus aureus (MRSA) and carbapenem-resistant Enterobacteriaceae (CRE). Furthermore, the combination of silver metal complexes with existing antimicrobial agents has shown synergistic effects, leading to enhanced antimicrobial activity. Organo-metallic compounds has shown interestingly research are for researchers, the OMC are widely used both stoichiometrically in research and industrial chemical reactions, as well as in the role of catalysts to increase the rates of such reactions, OMC include polymers, pharmaceuticals. The metalation of silver complexes with ligand salicyclic acid and yield was 2.5g. The OMC compound further taken study for Anti-Microbial activity on E. coli and Staphylococci species.

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