Changes in the Protein Content (Mg-Gr Wet Weight of the Tissue) in Different Tissues of Channa Punctatus on Exposure to Sub-Lethal and Lethal Concentrations of Chlorpyrifos Technical Grade For 24H

Author(s): Dr. M Sunanda

Abstract:

The protein content was significantly decreased in liver, kidney and muscle stated that the depletion of tissue protein content after 7 days exposure period may be due to increased proteolysis. This in turn will contribute to the presence of excess free amino acids which are directed to the tricarboxylic acid (TCA) cycle and further effective utilization of its products for metabolic activity. Under exposure to sub-lethal and lethal doses of chlorpyrifos technical grade and 20% EC, the total protein content was found to be decreased in all the tissues tested. Maximum decrease was noticed in gill and liver followed by muscle, brain and kidney at 8 days sub lethal exposure. In lethal 96 h exposure significant decrease was noticed in all the tissues. Maximum decrease was noticed in gill and liver followed by muscle, kidney and brain. The apparent decrease of total protein content under sub lethal and lethal exposure of chlorpyrifos may be due to the detoxification of enzymes. The decreased tendency of total proteins may also be due to metabolic utilization of the ketoacids in gluconeogenesis pathway for the synthesis of glucose or may be due to directing the synthesis of proteins from free amino acids (Schmidt Nielson, 1975). The decrease in protein content was more due to breakdown rather than retarded synthesis which is supported by the findings of Radhaiah (1988).

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