Comparative Study of Various Methods of Performing Cannizzaro Reaction and Calculating the Final Yield

Author(s): MR Chaya, Manoj SV, Rekhashree H and Pranav R Rao

Abstract:

The most often employed reaction in organic synthesis is Cannizzaro's reaction. Cannizzaro's response appears to be highly well-liked by the various universities due to its unique qualities. It can be carried out on a large or small scale and is covered in a variety of books and articles on organic synthesis.In the presence of a base, the aldehyde functional group without alpha hydrogen is transformed into carboxylic acid and alcohol. A study was carried out wherein three distinct experimental procedures were utilized to produce benzoic acid and benzoyl alcohol from the reaction between benzaldehyde and a strong base such as potassium hydroxide or sodium hydroxide. This report presents a comparative analysis of the total yield produced through three distinct experimental procedures. Mechanical stirring is the first technique, the second involves a hot water bath, and the third involves grinding. These techniques were also tested with two distinct concentrations of the same .The yields of products using two bases and three distinct processes were tallied and compared. When alcoholic sodium hydroxide was utilized as the base in the grinding process, the yield of the products increased; however, in the other two techniques that also used alcoholic sodium hydroxide, the yield of benzoic acid and benzyl alcohol was significantly lower.TLC and IR data are used to characterize every product that is obtained.

Keywords: Benzoic acid, benzyl alcohol, base, benzaldehyde, nucleophilic substitution.

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